A decorator of Venetian churches and palaces in the second half of the eighteenth century, Guarana is the last remaining direct heir of the Tiepolesque tradition. He was a founding member of the Venetian Accademia di Belle Arti and is said to have studied under Sebastiano Ricci, then with Giovanni Battista Tiepolo. In 1750 he completed frescoes for the interior of Ca' Rezzonico and, in 1780, for the church of San Tomà. He also painted for the church of San Teonisto in Treviso and the Villa Contarini in Cinto Euganeo and helped decorate the Villa Pisani at Stra. Other works were completed for the Palazzo Balbi, Palazzo Boldù a San Felice, Palazzo Erizzo a San Martino, Palazzo Michiel del Brusà, and Palazzo Mocenigo a San Stae.