Camilla Guiscardi  studied in Milan with Ernesta Bisi, and then in Turin with Pelagio Palagi. As early as 1823, she was mentioned in the records of the Brera Academy for her reproductions of works by Hayez, Correggio, Raphael, Luini, Guercino, Albani, and Sassoferrato, both in oil, watercolor, and pencil. She participated in the Brera exhibitions from 1821 to 1840 with various works, including miniatures and drawings for lithographs, including those for the volume Portraits of Living Italian Women Who Distinguished Themselves in Science, Letters, and the Fine Arts, published by Vassalli in 1839. In addition to being a painter, she was also an esteemed lithographer and portraitist, especially of notable personalities in Milan and beyond, including Silvio Pellico, Carlotta Marchionni, Pompeo Marchesi, Giovanni Migliara, Teresa Benincampi, and others. Guiscardi undertook study trips to Florence, where she furthered her skills under Giuseppe Bezzuoli, and Rome, and in the latter half of the 1830s, she arrived in Turin, where she settled and participated in the royal exhibitions at the Castello del Valentino. In 1842, she was appointed an honorary painter to King Charles Albert of Sardinia and she participated in the exhibitions of the Promotrice of Fine Arts in Turin with numerous works. On 21 April 1844 Camilla was elected Virtuosa di Merito in the Pontifical Academy of Fine Arts and Letters of the Virtuosi al Pantheon. Subsequently, she returned to her hometown Genoa, where she was welcomed as an academic of merit at the Ligurian Academy of Fine Arts. From 1851 to 1854, she participated in the exhibitions of the Promotrice of Fine Arts in Genoa. In 1855, she participated in the Borbonic Exhibition in Naples. Even in her later years, she never ceased her intellectual activity.